Researchers have developed a simple and versatile method for making artificial anti-cancer molecules that mimic the properties of one of the body's natural defence systems. The chemists, led by Professor Peter Scott at the University of Warwick, UK, have been able to produce molecules that have a similar structure to peptides which are naturally…
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Key to aging immune system: Discovery of DNA replication problem
There's a good reason people over 60 are not donor candidates for bone marrow transplantation. The immune system ages and weakens with time, making the elderly prone to life-threatening infection and other maladies, and a UC San Francisco research team now has discovered a reason why. "We have found the cellular mechanism responsible for the…
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Researchers eliminate HIV from cultured human cells for first time
HIV-1, the most common type of the virus that causes AIDS, has proved to be tenacious, inserting its genome permanently into its victims' DNA, forcing patients to take a lifelong drug regimen to control the virus and prevent a fresh attack. Now, a team of Temple University School of Medicine researchers has designed a way…
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Newly discovered gut virus lives in half the world’s population
Odds are, there's a virus living inside your gut that has gone undetected by scientists for decades. A new study led by researchers at San Diego State University has found that more than half the world's population is host to a newly described virus, named crAssphage, which infects one of the most common types of…
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Four-billion-year-old chemistry in cells today
Parts of the primordial soup in which life arose have been maintained in our cells today according to scientists at the University of East Anglia. Research published today in the Journal of Biological Chemistry reveals how cells in plants, yeast and very likely also in animals still perform ancient reactions thought to have been responsible for the…
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Biologist warn of early stages of Earth’s sixth mass extinction event
The planet's current biodiversity, the product of 3.5 billion years of evolutionary trial and error, is the highest in the history of life. But it may be reaching a tipping point. In a new review of scientific literature and analysis of data published in Science, an international team of scientists cautions that the loss and…
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People Use Just 8.2% of Their DNA, Study Finds
More than a decade has passed since the completion of the Human Genome Project, the international collaboration to map all of the "letters" in our DNA. The huge effort led to revolutionary genomic discoveries, but more than 10 years later, it's still unclear what percentage of the human genome is actually doing something important.…
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Marmoset sequence sheds new light on primate biology and evolution
A team of scientists from around the world led by Baylor College of Medicine and Washington University in St. Louis has completed the genome sequence of the common marmoset -- the first sequence of a New World Monkey -- providing new information about the marmoset's unique rapid reproductive system, physiology and growth, shedding new…
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Earth-like soils on Mars? Ancient fossilized soils potentially found deep inside impact crater suggest microbial life
Soil deep in a crater dating to some 3.7 billion years ago contains evidence that Mars was once much warmer and wetter, says University of Oregon geologist Gregory Retallack, based on images and data captured by the rover Curiosity. NASA rovers have shown Martian landscapes littered with loose rocks from impacts or layered by…
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The Origins and Evolution of the Ribosome
The evolution of the ribosome, a large molecular structure found in the cells of all species, has been revealed in unprecedented detail in a new study. Around 4 billion years ago, the first molecules of life came together on the early Earth and formed precursors of modern proteins and RNA. Scientists studying the origin of…
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