Thousands of genetic "dimmer" switches, regions of DNA known as regulatory elements, were turned up high during human evolution in the developing cerebral cortex, according to new research from the Yale School of Medicine. Unlike in rhesus monkeys and mice, these switches show increased activity in humans, where they may drive the expression of genes…
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Genetically speaking, mammals are more like their fathers
You might resemble or act more like your mother, but a novel research study from UNC School of Medicine researchers reveals that mammals are genetically more like their dads. Specifically, the research shows that although we inherit equal amounts of genetic mutations from our parents -- the mutations that make us who we are and…
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‘Nightmare Bacteria’ Require Old and New Weapons
"Superbug" bacteria that are resistant to antibiotics have the potential to create a nightmare scenario for modern medicine, but experts are hopeful that doctors will be able to slow the spread of these scary infections, by both traditional means and new innovations. Recently, a Los Angeles hospital announced that more than 100 patients treated there…
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DNA evidence shows surprise cultural connections between Britain and Europe 8,000 years ago
The ancient British were not cut off from Europeans on an isolated island 8,000 years ago as previously thought, new research suggests. Researchers found evidence for a variety of wheat at a submerged archaeological site off the south coast of England, 2,000 years before the introduction of farming in the UK. The team argue that…
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‘Big Brain’ Gene Found in Humans, Not Chimps
A single gene may have paved the way for the rise of human intelligence by dramatically increasing the number of brain cells found in a key brain region. This gene seems to be uniquely human: It is found in modern-day humans, Neanderthals and another branch of extinct humans called Denisovans, but not in chimpanzees. By…
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Scientists announce anti-HIV agent so powerful it can work in a vaccine
In a remarkable new advance against the virus that causes AIDS, scientists from the Jupiter, Florida campus of The Scripps Research Institute (TSRI) have announced the creation of a novel drug candidate that is so potent and universally effective, it might work as part of an unconventional vaccine. The research, which involved scientists from more than…
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New antibiotic holds promise against antibiotic-resistant infections
Estimates of deaths from methicillin-resistant Staphylococcus aureus (MRSA) in the United States range upwards of 19,000 annually. Around 1960, when Staphylococcus aureus developed resistance to first-generation penicillin, methicillin and other second-generation beta-lactam antibiotics were adopted to fight the illness. The modern variants of the bacterium have developed resistance to the four drugs now used to…
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Telomere extension turns back aging clock in cultured human cells, study finds
A new procedure can quickly and efficiently increase the length of human telomeres, the protective caps on the ends of chromosomes that are linked to aging and disease, according to scientists at the Stanford University School of Medicine. Treated cells behave as if they are much younger than untreated cells, multiplying with abandon in the…
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DNA clock helps to get measure of people’s lifespans
Scientists have identified a biological clock that provides vital clues about how long a person is likely to live. Researchers studied chemical changes to DNA that take place over a lifetime, and can help them predict an individual's age. By comparing individuals' actual ages with their predicted biological clock age, scientists saw a pattern emerging.…
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Nanoparticle drug stops cancer’s spread in mice
When a person dies from cancer, the culprit is usually not the original tumor but rather the cancerous cells that spread throughout the body and replicate in distant organs, a process called metastasis. Researchers have long known that metastasizing cancer cells slip their bonds and avoid immune detection by altering the sugars on their surfaces.…
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